Otorhinolaryngologic Manifestations of Wegener's Granulomatosis

Aleksandra Aleksic, Zorica Novakovic, Dalibor Vranjes, Miroslav Petkovic, Vesna Tomic-Spiric


Wegener's granulomatosis is a clinical form from the group of systemic vasculitis and glomerulonephritis ANCA. This disease of unknown etiology is characterized by necrotizing granulomatosis angiitis. Otorhinolaryngologic symptoms are the first symptoms of Wegener's granulomatosis in 80 to 95% of cases. Early diagnosis is very important as it enables early intensive immunosuppressive therapy, which can lead to permanent remission. Discovery of c-ANCA enables quick noninvasive serological diagnosis. The case described is a female patient suffering from Wegener's granulomatosis, aged 48, from the occurrence of the first symptoms, through diagnostic and therapy procedures until the final diagnosis was made.


otorhinolaryngologic symptoms, Wegener's granulomatosis, c-ANCA,

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DOI: 10.5457/ams.v40i2.161