Role of Multi-Detector Computed Tomography in Assessing Anatomical Site Variation of Appendix in Patients with Appendicitis
Abstract
Introduction: The appendix is a blind-ended tubular structure arising from the cecum with diameter of less than 6 mm. Acute appendicitis (AA) is considered as a common disease in young patients and may occur in any age. The use of biochemical markers and urine analysis may lack specificity for AA diagnosis. Thus, the aim is to assess the feasibility of multi-detector computed tomography (MDCT) in diagnosing and differentiating kinds of appendicitis.
Methods: 121 consecutive patients (8.30% female, 91.70% male), with a mean age of 23.86 ± 10.86 years who were operated on for the suspicion of AA, were included in this study. Recruited patients were classified as false negative (FN) group and true positive (TP) group based on lab result and both clinical decision, symptoms and MDCT findings. Mann-Whitney U test was used to compare whether there is a difference in the dependent variable for two independent groups (FN and TP). A two-sided p-value > 0.05 was considered significant.
Results: There was a statistical difference has been observed between the FN and TP groups (p=0.005) with respect to white blood (WBC) counts. However, those groups were not statistically different from each other (p=0.16) as a function of appendix diameter. There was a linear relation between WBC counts and appendix diameter > 10 mm.
Conclusion: MDCT is highly accurate in diagnosing acute appendicitis. US is a “first-pass” recommended approach in diagnosing acute appendicitis. Appendix diameter greater than 10 mm is linearly correlated with white blood cell counts.
Keywords
References
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DOI: 10.5457/ams.v55i1.816