Brain natriuretic peptide and troponin I in acute myocardial infarction

Abstract

Myocardial infarction, in the diagnostic and therapeutic aspects, is of one of the great social and medical problems. Clinical diagnosis requires the presence of clinical symptoms in combination with indirect indicators of cardiac necrosis, such as biochemical markers- enzymes, electrocardiographic (ECG) and echocardiography findings. Assessment of heart failure by determining markers of myocardial damage is very significant challenge in the process of clinical assessment of patients with myocardial infarction, for further diagnosis, treatment and prognosis. Heart failure occurs in all patients with myocardial infarction, to a lesser or greater extent. Bearing in mind that, a myocardial infarction involving the anterior wall of the heart has worse prognosis, the subject of interest of this study is whether the markers of myocardial damage will be higher in patients with this localization of myocardial infarction. It was interested too, in whether it is possible to find elevated markers of myocardial damage- failure indicators, brain natriuretic peptide, in corelation with clinical signs of cardiac insuficiency.