Otorhinolaryngologic Manifestations of Wegener's Granulomatosis

Authors

  • Aleksandra Aleksic ENT Clinic.Clinical center Banja Luka
  • Zorica Novakovic ENT Clinic.Clinical center Banja Luka
  • Dalibor Vranjes ENT Clinic.Clinical center Banja Luka
  • Miroslav Petkovic Department of Microbiology and Immunology, School of Medicine, University of Banja Luka
  • Vesna Tomic-Spiric Institute for allergy and clinical immunology.Clinical center Serbia.Belgrade

DOI:

https://doi.org/10.5457/ams.v40i2.161

Keywords:

otorhinolaryngologic symptoms, Wegener's granulomatosis, c-ANCA,

Abstract

Wegener's granulomatosis is a clinical form from the group of systemic vasculitis and glomerulonephritis ANCA. This disease of unknown etiology is characterized by necrotizing granulomatosis angiitis. Otorhinolaryngologic symptoms are the first symptoms of Wegener's granulomatosis in 80 to 95% of cases. Early diagnosis is very important as it enables early intensive immunosuppressive therapy, which can lead to permanent remission. Discovery of c-ANCA enables quick noninvasive serological diagnosis. The case described is a female patient suffering from Wegener's granulomatosis, aged 48, from the occurrence of the first symptoms, through diagnostic and therapy procedures until the final diagnosis was made.

Author Biography

Aleksandra Aleksic, ENT Clinic.Clinical center Banja Luka

Klinika za bolesti uha, grla i nosa

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Published

2011-11-23

Issue

Section

Case reports