Monitoring the response to non- adjuvant chemotherapy in patients with breast cancer using ultrasound: radiology pathology correlation
DOI:
https://doi.org/10.5457/ams.v51i1-2.558Keywords:
Ultrasound, RECIST criteria, breast cancer, non-adjuvant chemotherapy.Abstract
Objective. The aim of this study was to determine whether there is a correlation between the size of ultrasound- measured malignant lesions in the breast in patients undergoing non- adjuvant chemotherapy using RECIST criteria and sizes of malignant lesions on definitive histopathological finding. Patients and methods. The study was retrospective study and was conducted on 32 women aged 37-69 years of age at the period of may 2017th until march 2019, mammograms and ultrasound suspected breast cancer (radiological findings is concludedObjective. The aim of this study was to determine whether there is a correlation between the size of ultrasound- measured malignant lesions in the breast in patients undergoing non- adjuvant chemotherapy using RECIST criteria and sizes of malignant lesions on dthe period of may 2017th until march 2019, mammograms and ultrasound suspected breast cancer (radiological findings is concluded as BI RADS 4 and 5) and needle biopsy under control of ultrasound confirmed the diagnosis of breast cancer. Patients with metastases present were excluded from the study. Response to non- adjuvant chemotherapy was followed by ultrasound after the third and sixth cycles, after sixth cycles the patients underwent surgery.To calculate the correlation was used Pearson's correlation coefficient. The difference in the values of p less than 0.05 (p <0.05) was considered statistically significant. Results. Complete response according to RECIST criteria was ultrasonically detected in 33,33 % of patients with estrogen, progesterone negative, and HER2 positive cancers and 33,33% of patients with estrogen positive, progesterone and HER2 negative cancers which correlates with the histopathological complete response. Conclusion. There is a  correlation between ultrasound measured tumor lesions using RECIST criteria and measured tumor lesions on histopathological speci
Downloads
Published
Issue
Section
License
Copyright transfer
The listed authors warrant that they are the authors and sole owners of the submitted manuscript. The authors also warrant that the work is original; that it has not been previously published in print or electronic format and is not under consideration by another publisher or electronic medium; that it has not been previously transferred, assigned, or otherwise encumbered; and that the authors have full power to grant such rights. With respect to the results of this work, the manuscript of this or substantially similar content will not be submitted to any other journal until the review process in the Acta Medica Salinianana has been officially completed (acceptance or rejection of the manuscript). The paper will not be withdrawn from the review process by the Acta Medica Saliniana Editorial Board until the review process is completed. The authors will comply with the requests of the Acta Medica Saliniana Editors and reviewers to improve the paper for publication. The eventual disagreements will be submitted in a written form; the authors are aware that the disagreement(s) with the Acta Medica Saliniana requests may result in the rejection of the manuscript. The authors hereby grant to the Acta Medica Saliniana the right to edit, revise, abridge, and condense the manuscript. If the manuscript is accepted for publication in the Acta Medica Saliniana, the authors hereby transfer the copyright of the paper to the Acta Medica Saliniana. The authors permit the Acta Medica Saliniana to allow third parties to copy any part of the journal without asking for permission, provided that the reference to the source is given. For papers with more than one author: All other co-authors agree to allow the corresponding author to make decisions regarding prepublication release of the information in the paper to the media, federal agencies, or both.
